Early and late neurodegeneration and memory disruption after intracerebroventricular streptozotocin
نویسندگان
چکیده
منابع مشابه
Early and late neurodegeneration and memory disruption after intracerebroventricular streptozotocin
Glucose metabolism and insulin signaling disruptions in the brain have been proposed as a likely etiology of Alzheimer's disease. The aim of the present study was to investigate the time course of cognitive impairments induced by intracerebroventricular injection of streptozotocin (STZ) in rats and correlate them with the ensuing neurodegenerative process. Early and late effects of STZ were eva...
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متن کاملEarly and late consolidation and reconsolidation of memory in the prelimbic cortex
Rats can learn to forage among olfactory cues to associate one with reward in only 3 massed trials. The learning is achieved in less than 10 min and results in a memory trace lasting at least 1wk week. To study the neuro-anatomical circuits involved in the memory formation we used immunoreactivity to the immediate early gene c-fos as a marker for neuronal activity induced by the learning. The p...
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ژورنال
عنوان ژورنال: Physiology & Behavior
سال: 2012
ISSN: 0031-9384
DOI: 10.1016/j.physbeh.2012.06.019